scREAD A Single-cell RNA-Seq Database for Alzheimer's Disease
General information
Overview

scREAD Data ID: AD00205

Species: Human

Region: Entorhinal Cortex

Condition: Disease

Braak stage: 2

Gender: Male

Age: 50-91 years

Datasets from the same experiment
Dataset information

Number of AD associated cells: 25492

Number of control-like cells: 0

Number of identified cell types: 1

Dataset source:

Title: Molecular characterization of selectively vulnerable neurons in Alzheimer’s Disease

Methodology: Single-nucleus RNA-seq

Protocol: 10x Genomics

GEO/synapse number: GSE147528

Pubmed ID: NA

Citation: Leng K, Li E, Eser R, et al. Molecular characterization of selectively vulnerable neurons in Alzheimer’s Disease. bioRxiv; 2020. 10.1101/2020.04.04.025825.

Cell clustering

Cell type & subcluster:

Gene expression

Point size:

4
Differential expression (DE) / Gene set enrichment

Group:

Find differentially expressed genes in each cell type by comparing it to all of the others.

Cell type of interest:

Log2 fold-change cutoff:

0.5

Adjusted p-value cutoff:

10^-6
10^-5
10^-4
10^-3
0.01
0.05
0.1
1
DE direction:
ADGRV1 2.45364 0.611 0.063 0.00e+0
SLC1A2 2.43446 0.716 0.13 0.00e+0
RNF219-AS1 2.27422 0.502 0.036 0.00e+0
GPC5 2.12119 0.691 0.129 0.00e+0
GJA1 2.02879 0.383 0.017 0.00e+0
GFAP 2.00614 0.509 0.073 0.00e+0
FGFR3 1.91817 0.428 0.042 0.00e+0
CLU 1.86437 0.682 0.196 0.00e+0
SDC4 1.83865 0.298 0.013 0.00e+0
PITPNC1 1.80587 0.583 0.134 0.00e+0
APOE 1.78373 0.534 0.084 0.00e+0
ATP1A2 1.78373 0.454 0.056 0.00e+0
AQP4 1.76791 0.328 0.015 0.00e+0
EMX2 1.71731 0.256 0.006 0.00e+0
GLIS3 1.71545 0.366 0.036 0.00e+0