scREAD Data ID: AD00110
Species: Human
Region: Prefrontal cortex
Condition: Disease
Braak stage: 1, 4 - 5
Gender: Female
Age: 77-90+ years
Number of AD associated cells: 15300
Number of control-like cells: 2651
Number of identified cell types: 7
Title: Human_and_Mouse Single-Nucleus Transcriptomics Reveal TREM2-dependent_and_TREM2-independent Cellular Responses in Alzheimer's Disease
Methodology: Single-nucleus RNA-seq
Protocol: 10x Genomics
GEO/synapse number: syn21125841
Pubmed ID: 31932797
Citation: Zhou Y, Song WM, Andhey PS, Swain A et al. Human_and_mouse single-nucleus transcriptomics reveal TREM2-dependent_and_TREM2-independent cellular responses in Alzheimer’s disease. Nat Med 2020 Jan;26(1):131-142.
Cell type & subcluster:
Gene expression
Point size:
Please enter a gene symbol.
Group:
Cell type of interest:
Log2 fold-change cutoff:
Adjusted p-value cutoff:
SLC1A2 | 2.87611 | 0.891 | 0.278 | 0.00e+0 |
ATP1A2 | 2.50032 | 0.845 | 0.153 | 0.00e+0 |
ADGRV1 | 2.47457 | 0.713 | 0.093 | 0.00e+0 |
AQP4 | 2.46597 | 0.756 | 0.108 | 0.00e+0 |
GJA1 | 2.34641 | 0.686 | 0.06 | 0.00e+0 |
GFAP | 2.29681 | 0.848 | 0.129 | 0.00e+0 |
GLUL | 2.10638 | 0.857 | 0.32 | 0.00e+0 |
COL5A3 | 2.04411 | 0.597 | 0.07 | 0.00e+0 |
AHNAK | 2.03573 | 0.705 | 0.047 | 0.00e+0 |
ATP1B2 | 2.00043 | 0.71 | 0.159 | 0.00e+0 |
SLC25A18 | 1.92909 | 0.64 | 0.052 | 0.00e+0 |
CST3 | 1.92787 | 0.813 | 0.254 | 0.00e+0 |
TPD52L1 | 1.89208 | 0.612 | 0.075 | 0.00e+0 |
HIF3A | 1.83805 | 0.666 | 0.068 | 0.00e+0 |
SLC14A1 | 1.79017 | 0.521 | 0.013 | 0.00e+0 |