scREAD Data ID: AD00105
Species: Human
Region: Prefrontal cortex
Condition: Disease
Braak stage: 3 - 5
Gender: Female
Age: 75-90+ years
Number of AD associated cells: 11542
Number of control-like cells: 1644
Number of identified cell types: 6
Title: Single-cell Transcriptomic Analysis of Alzheimer's Disease
Methodology: Single-nucleus RNA-seq
Protocol: 10x Genomics
GEO/synapse number: syn18485175
Pubmed ID: 31042697
Citation: Mathys, H., Davila-Velderrain, J., Peng, Z. et al. Single-cell transcriptomic analysis of Alzheimer’s disease. Nature 570, 332–337 (2019). 10.1038/s41586-019-1195-2
Cell type & subcluster:
ARI score: 0.9827172
Gene expression
Point size:
Please enter a gene symbol.
Group:
Cell type of interest:
Log2 fold-change cutoff:
Adjusted p-value cutoff:
GJA1 | 2.31193 | 0.808 | 0.012 | 0.00e+0 |
SLC1A2 | 2.30622 | 0.961 | 0.154 | 0.00e+0 |
GPR98 | 2.25969 | 0.92 | 0.125 | 0.00e+0 |
AQP4 | 2.11009 | 0.742 | 0.028 | 0.00e+0 |
ATP1A2 | 2.10408 | 0.801 | 0.059 | 0.00e+0 |
RNF219-AS1 | 2.08067 | 0.696 | 0.033 | 0.00e+0 |
RANBP3L | 2.03619 | 0.668 | 0.021 | 0.00e+0 |
HIF3A | 1.98214 | 0.763 | 0.045 | 0.00e+0 |
GPC5 | 1.96967 | 0.955 | 0.216 | 0.00e+0 |
RFX4 | 1.96139 | 0.674 | 0.044 | 0.00e+0 |
SLC1A3 | 1.93519 | 0.921 | 0.1 | 0.00e+0 |
TPD52L1 | 1.93295 | 0.734 | 0.057 | 0.00e+0 |
LINC00499 | 1.9288 | 0.554 | 0.006 | 0.00e+0 |
COL5A3 | 1.9076 | 0.68 | 0.045 | 0.00e+0 |
FGFR3 | 1.90278 | 0.621 | 0.01 | 0.00e+0 |